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Dermal & Extracellular Matrix

Copper Chelation Dynamics & Fibroblast Procollagen Remodeling

Analytical laboratory profiles of copper-binding tripeptides studied for coordinate complex formation, matrix metalloproteinase (MMP) homeostasis, decorin synthesis, and dermal fibroblast motility.

Signaling Focus: Copper (Cu2+) coordination geometry, TGF-beta signaling modulation, procollagen Type I and III transcription, MMP regulation.
1 Compound Monograph Indexed

Reagents in this Signaling Category

Human Trial DataCAS 49557-75-7

GHK-Cu

Copper Tripeptide-1 Complex (Gly-His-Lys:Cu2+)

C14H24CuN6O4403.92 g/molDermal & Extracellular Matrix

GHK-Cu is a naturally occurring tripeptide-copper coordinate complex identified in human plasma. Investigated in UK cosmetic chemistry and cellular biology laboratories for its regulation of matrix metalloproteinases, decorin, and collagen I/III biosynthesis.

Verified UK Sourcing Partners:
PharmaGrade Store (≥99.3% (HPLC))Direct Peptides (≥99.1% (HPLC))Direct Sarms (≥98.7% (HPLC))Peptide Works (≥99.0% (HPLC))PharmaLab Global (≥99.5% (HPLC))
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