Metabolic & Incretin Signaling
Dual Incretin Receptor Co-Agonism & Lipolytic Energy Dynamics
Biochemical reference dossiers for synthetic unimolecular co-agonists and lipolytic peptide sequences investigated in GLP-1, GIP, and beta-3 adrenergic receptor pathways controlling cellular energy homeostasis.
Reagents in this Signaling Category
AOD-9604
Human Growth Hormone C-Terminal Fragment (Tyr-hGH177-191)
AOD-9604 is a synthetic hexadecapeptide analog representing the lipolytic C-terminal domain of human growth hormone (hGH 177-191) with an added tyrosine residue. Investigated in UK metabolic and adipose tissue laboratories for beta-3 adrenergic receptor signaling without diabetogenic IGF-1 elevation.
Tirzepatide
Dual GIP and GLP-1 Receptor Co-Agonist 39-AA Synthetic Peptide
Tirzepatide is a synthetic 39-amino-acid unimolecular dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor co-agonist conjugated to a C20 fatty diacid moiety. Studied extensively in UK biochemical and pharmaceutical research for receptor affinity dynamics.
Semaglutide
Acylated GLP-1 Analogue (31-AA Chain with C18 Diacid Spacer)
Semaglutide is a synthetic long-acting glucagon-like peptide-1 (GLP-1) receptor agonist modified at position 8 with alpha-aminoisobutyric acid (Aib) and acylated at Lys26 with a C18 fatty diacid chain. Studied in UK endocrinology and metabolic research as a classical mono-incretin reference standard.